

GlaxoSmithKline and SuperGen entered into a collaboration to discover and develop cancer therapeutics based on epigenetic targets in a transaction with a potential value of more than $380 million for SuperGen, the companies said Monday.
The UK drugmaker could make milestone payments that may exceed $375 million, and pay royalties on any approved products. SuperGen will be responsible for early development of potential compounds, while GlaxoSmithKline will have the option to further develop any drugs and commercialise products on a global basis.
According to SuperGen, epigenetic processes are "believed to play a central role in the development and progression of almost all cancers."